87 comments
LinguaBrowse · 12 days ago
I studied an BSc in genetics and none of our lectures or textbooks presented mitochondria any differently from the classic bean shape they introduce in school. This is surely old news to folks who specialise in mitochondria, but it's easy to miss out on these fundamentals even if you've studied in a relevant area at degree level, because there's just so much to know in biology.

In fact, it's one of those fields where the more you learn, the more you realise we'll never reach a satisfactory understanding in our lifetime. You could chuck an endless supply of PhD students at every constituent domain for generations and still feel like you've scarcely scratched the surface of the many things there are to question.

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bentt · 12 days ago
Mitochondria are a descendant of early bacteria which infiltrated an Archaea cell, traded genes, and started replicating with it, forming a new organism about 1.5bn years ago.

The wild part is that all mitochondria are descended from that single event.

This was a rather controversial theory called Endosymbiosis and it was pioneered by Lynn Margulis. Now it is widely accepted.

https://evolution.berkeley.edu/it-takes-teamwork-how-endosym...

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gcanyon · 12 days ago
Does anyone here have a sense of what time frame the video covers? Like, is that real-time and mitochondria are continuously mildly active? Is it vastly slowed down and mitochondria are ripping around in our cells like madmen? Is it vastly sped up and mitochondria are actually relatively static, slow movers?

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8-prime · 13 days ago
Mitochondria are so absurdly more complex and interesting than what is mostly taught in schools. Awesome video!
Madmallard · 12 days ago
Really sucks that antibiotics, especially bacteriocidal ones, appear to target mitochondria as if they were bacteria. This mistargetting causes sometimes severe and long-lasting side effects.

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